Table 2.
Mutations characterized in the different genes related to resistance to malaria drugs analyzed
| Sample number | Nationality | DHPS genotype | DHFR genotype | CytB genotype | MDR genotype | CRT genotype | K13 genotype | |
|---|---|---|---|---|---|---|---|---|
| N86Y | D1246Y | |||||||
| 1 | Nigerian | S436A | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
| 2 | Sudanese | S436A, K540E | N51I, C59R, S108N | Wild | Wild | Wild | M74I, N75E, K76T | Wild |
| 3 | Saudi | S436A | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
| 6 | Ethiopian | K540E | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
| 10 | Saudi | K540E | N51I, S108N | Wild | N86Y | Wild | Wild | Wild |
| 15 | Sudanese | S436A | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
| 16 | Sudanese | S436A | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
| 17 | Saudi | K540E, A581G | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
| 18 | Sudanese | NA | NA | NA | NA | Wild | Wild | NA |
| 19 | Sudanese | S436A | N51I, C59R, S108N | Wild | Wild | Wild | M74I, N75E, K76T | Wild |
| 20 | Indian | S436A, K540E | N51I, S108N | Wild | N86Y | Wild | M74I, N75E, K76T | Wild |
| 21 | Sudanese | A437G | N51I, S108N | Wild | Wild | Wild | Wild | Wild |
| 26 | Saudi | – | N51I, C59R, S108N | Wild | N86Y | Wild | M74I, N75E, K76T | Wild |
NA no amplification was obtained after several trials