Table 2.
Demographic and clinical characteristics of infected children
| Characteristic | Single HAdV (n = 56) |
HAdV- viruses (n = 79) |
viruses-Typical Bacteria (n = 19) |
viruses–Atypical Bacteria (n = 18) |
|---|---|---|---|---|
| Gender(male) | 37(66.07) | 56(70.90) | 10(52.63) | 7(38.90)ce |
| age (months) IQR | 14(10–35.25) | 12(8–25) | 11(6–12)b | 18.5(12–38.25)ef |
| Age group | ||||
| < 6 | 7(12.50) | 10(12.66) | 4(21.05) | 0 |
| 6–23 | 25(44.64) | 44(55.70) | 14(73.68)b | 10(55.56) |
| 24–60 | 20(35.71) | 21(26.58) | 1(5.26)bd | 5(27.78)f |
| > 60 | 4(7.14) | 4(5.06) | 0 | 3(16.67)e |
| Length of stay, days | ||||
| Median (IQR) | 8.5(6–10) | 8(6–10) | 10(8–13)bd | 7(6–8.25)f |
| Mean ± SD | 8.52 ± 3.53 | 8.50 ± 4.53 | 10.68 ± 4.41 | 7.44 ± 2.41 |
| Duration of fever (days) | ||||
| Median (IQR) | 6(4–8) | 5.5(3–7) | 8(4.5–10.5)d | 5(3–7.5) |
| Mean ± SD | 6.94 ± 4.32 | 5.89 ± 4.77 | 8.00 ± 4.98 | 5.31 ± 2.96 |
| Cough | 56(100) | 79(100) | 19(100) | 18(100) |
| Fever | 49(87.50) | 62(78.48) | 14(73.68) | 16(88.89) |
| Diarrhea | 8(14.29) | 15(18.99) | 6(31.58) | 2(11.11) |
| Wheezing | 20(35.70) | 37(46.84) | 12(63.16)b | 4(22.22)f |
| Vomiting | 11(19.64) | 15(18.99) | 2(10.53) | 2(11.11) |
| Outcome | ||||
| Disease severity of CPA | ||||
| Mild | 25(44.64) | 53(67.09)a | 11(57.89) | 17(94.44)cef |
| Severe | 14(25.00) | 14(17.72) | 4(21.05) | 1(5.56) |
| Very severe | 17(30.36) | 12(15.19)a | 4(21.05) | 0c |
| Admission to PICU | 8(14.29) | 19(24.05) | 4(21.05) | 0e |
| supplemental oxygen requirement | 12(21.43) | 18(22.78) | 5(26.32) | 0f |
| HAdV load from NPAs (log 10 copies/mL) | 3.23 ± 1.87 | 3.25 ± 2.12 | 3.10 ± 2.16 | 2.60 ± 1.35 |
aP < 0.05, for comparison of single HAdV infections with combined virus-virus infections
bP < 0.05, for comparison of single HAdV infections with combined virus-typical bacterial infections
cP < 0.05, for comparison of single HAdV infections with combined virus-atypical bacterial infections
dP < 0.05, for comparison of virus-virus infections with virus-typical bacterial infections
eP < 0.05, for comparison of virus-virus infections with virus-atypical bacterial infections
fP < 0.05, for comparison of virus-typical bacteria with virus-atypical bacterial infections