TABLE 3.

Mixed-Effect Models Demonstrating Variance of Hospital Effect After Controlling for Patient-Level^a and Hospital-Level^b Factors

Variable	Variance of Hospital Level Random Effectc	95% CI of Variance
Antipseudomonal antibiotics
Hospital alone	0.030	0.014–0.064
Hospital plus patient factors	0.029	0.014–0.062
Hospital plus hospital factors	0.021	0.009–0.050
Hospital plus patient and hospital factors	0.022	0.010–0.051
Gram-positive antibiotics
Hospital alone	0.148	0.070–0.314
Hospital plus patient factors	0.141	0.065–0.305
Hospital plus hospital factors	0.136	0.063–0.294
Hospital plus patient and hospital factors	0.129	0.060–0.290
Carbapenems
Hospital alone	0.560	0.266–1.180
Hospital plus patient factors	0.534	0.247–1.157
Hospital plus hospital-level factors	0.438	0.198–0.966
Hospital plus patient and hospital factors	0.451	0.202–1.007

^aPatient-level factors include age, sex, race, diagnosis, disease status, donor type, graft source, recipient CMV status and days of severe illness.

^bHospital-level factors include hospital volume, proportions female, nonwhite race, and public insurance.

^cP value for all reported variances < .001.