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. 2018 Sep 6;7:963. Originally published 2018 Jun 28. [Version 2] doi: 10.12688/f1000research.15386.2

Table 1. Intra-species major histocompatibility complex (MHC) variation differs among teleost fishes.

This table shows the lowest percentages of amino acid sequence identities between membrane-distal domains (α1+α2 for MHC I, α1 for MHC IIA, β1 for MHC IIB) of same category MHC molecules found between reported sequences of the same species. In some species no genes for particular categories were found (black boxes), while in other instances only one seemingly intact gene sequence was found (1 sequence) or only pseudogenes were found (pseudogene). A more detailed explanation of this table is provided in Supplementary File 3.

Species Neoteleostei
Zebrafish Salmon Medaka Fugu Stickleback Tilapia Cod
MHC category (Danio
rerio)
(Salmo salar) (Oryzias
latipes)
(Takifugu
rubripes)
(Gasterosteus
aculeatus)
(Oreochromis
niloticus)
(Gadus
morhua)
MHC class I U classical 40% 47% 52% 75% 76% 52% 58%
U all 27% 38% 32% 29% 62% 27% 58%
Z 70% 84% 84% 1 sequence 1 sequence 78% 89%
L 27% 51% 1 sequence
P pseudogene 85% 1 sequence
S 99%
MHC class II DA IIA 34% 84% 48% 72% 64% 39%
DA IIB 34% 76% 56% 76% 57% 46%
DB IIA 23% 20% 20% 1 sequence 21%
DB IIB 31% 25% 26% 1 sequence 22%
DE IIA 99%
DE IIB 99%