Skip to main content
. Author manuscript; available in PMC: 2018 Aug 8.
Published in final edited form as: J Int Neuropsychol Soc. 2014 Jan;20(1):113–122. doi: 10.1017/S1355617713001203

Table 2.

Brain regions showing statistically greater task-related activation in individuals with autism or matched typically developing control participants

Passive viewing of visual movement Right hemisphere
Left hemisphere
Peak F value X Y Z Volume Peak F value X Y Z Volume
Greater in autism
Middle frontal gyrus (MFG) 4.34 −45 35 15 760
Posterior intraparietal sulcus (IPS) 7.11 −27 −53 58 344 4.44 23 −63 56 248
Precuneus 3.84 −16 −64 52 608 –
Lateral cerebellum 5.31 25 −41 −43 2448
Medial temporal gyrus (V5) 4.73 −47 −65 7 1376 3.65 41 −79 14 88
Visual cortex (V1/V2) 6.73 −5 −71 0 1000 9.40 5 −83 4 1968
Greater in TD
Frontal eye field (FEF) 6.37 −42 −6 58 456 4.80 39 1 56 664
Supplementary motor area (SMA) 5.91 −5 −29 58 128
Superior frontal gyrus (SFG)/middle frontal gyrus (MFG) 6.43 −39 37 38 2024 5.64 31 29 46 2280
Posterior intraparietal sulcus (IPS) 4.44 33 −69 48 1104
Lateral cerebellum 7.54 19 −80 −27 904
Visual cortex (V1/V2) 4.53 17 −83 −16 480
Posterior superior temporal sulcus 5.01 −47 −25 2 464
Visual pursuit tracking Right hemisphere
Left hemisphere
Peak F value X Y Z Volume Peak F value X Y Z Volume
Greater in autism
Anterior intraparietal sulcus (IPS)/superior parietal lobule (SPL) 6.74 −25 −49 54 376 6.33 37 −49 56 880
Precuneus 4.74 14 −63 54 360
Lateral cerebellum 4.06 −13 −83 −30 392 4.30 15 −79 −40 464
Visual cortex (V1/V2) 3.74 −3 −87 −2 144 5.60 7 −98 8 408
Greater in TD
Frontal eye field (FEF) 4.49 −34 −13 64 808 4.83 41 −8 34 256
Supplementary eye field (SEF) 4.37 3 −3 48 272
Posterior intraparietal sulcus (IPS) 4.42 −27 −65 42 456 5.19 38 −59 50 2176
Medial temporal gyrus (V5) 8.53 −52 −57 −2 792 5.09 49 −73 −14 472

Note. This table shows the F value for the peak activation in each region of interest and its corresponding coordinates in Talairach stereotaxic space, as well as the volume (mm3) of tissue in regions of interest in which there was statistically greater activation in one group relative to the other. Since clusters of activation identified by the contiguity threshold sometimes extended beyond pre-determined regions of interest, reported volumes of activation in regions of interest are in some cases less than the cluster volume required to identify significant effects.