. Author manuscript; available in PMC: 2019 Jan 30.

Published in final edited form as: Nat Struct Mol Biol. 2018 Jul 30;25(8):669–676. doi: 10.1038/s41594-018-0094-9

Table 1. Repeat instability in Gc-r clones originated from cell lines containing CGG153-HyTK cassettes in the RL5 locus.

71% of Gc-r clones had changes in the length of the CGG repeat across six experimental trials.

N of Trials	CGG153-HyTK clone	Cassette orientation	Total number of Gc-r clones	Number and percentile of Gc-r clones with repeat instability	Repeat length changes in unstable clones
2	c2-29-1	A	58	31 (53%)*	9 expansions (15%) 22 contractions (38%)
2	c2-29-2	A	57	43 (75%)	15 expansions (26%) 28 contractions (49%)
1	c3-1	A	113	89 (80%)	68 expansions (60%) 21 contractions (20%)
1	c2-38	B	15	9 (60%)	3 expansions (20%) 6 contractions (40%)
Total:			243	172 (71%)	95 expansions (39%) 77 contractions (32%)