Figure 3.

(left) Bound state lifetimes (computed from Eq. (6) and Eq. (14)) as a function of the alignment between the incoming molecule and the fibril. The lifetime is maximized in the perfectly aligned state (R = 0) and drops exponentially as |R| increases. (right) Capture probabilities (Eq. (18)) of the uniform sequence as a function of the alignment. As the concentration increases, the rate of monomer collisions with the fibril end increases from r_on=10⁴ s⁻¹ (black), 10⁶ s⁻¹ (red), to 10⁸ s⁻¹ (blue). The capture probability transitions from a sharply peaked function at R = 0 to a broad plateau. The plateau indicates that many mis-registered molecules are incorporated in the fibril. ε₀ = 0.5, L = 20