Table 5. Association of UCP polymorphisms with cardiovascular risk factors.

		UCP2 A55V			UCP2 -866			UCP3 -55C/T
	Model	Pc	OR	95%CI	Pc	OR	95%CI	Pc	OR	95%CI
BMI >30 kg/cm2	Recessive	0.003	1.64	1.30-2.06	0.063	1.87	1.18-2.45	0.540	2.50	0.42-12.76
	Additive	0.001	1.44	1.15-1.80	0.030	1.45	1.16-1.81	0.197	1.60	0.88-2.09
HT >140 mmHg	Recessive	0.069	1.84	0.99-3.42	0.221	2.03	1.05-3.93	0.007	6.53	5.16-8.27
	Additive	0.052	1.33	1.00-1.77	0.049	1.72	1.23-2.41	0.011	6.55	5.21-8.31
Hypercholesterolemia > 160 mg/dL	Recessive	0.051	0.23	0.15-0.36	0.006	3.41	2.22-5.26	0.007	2.53	1.92-3.44
	Additive	0.062	0.22	0.18-0.28	0.038	1.65	1.26-2.17	0.011	2.56	1.95-3.49
LDL-C >130 mg/dL	Recessive	0.070	0.23	0.14-0.37	0.096	1.96	1.22-3.16	0.618	2.00	0.42-9.51
	Additive	0.015	3.01	2.40-3.78	0.030	0.14	0.10-0.19	0.236	3.03	1.94-4.63
Hypertriglyceridemia >150 mg/dL	Recessive	0.066	0.57	0.39-0.84	0.151	2.63	1.76-3.92	0.006	1.99	1.61-2.53
	Additive	0.059	0.53	0.44-0.65	0.100	2.20	1.81-2.67	0.010	2.01	1.69-2.62
Hypoalphalipoproteinemia < 40 mg/dL	Recessive	0.168	1.56	1.07-2.26	0.910	1.04	0.71-1.52	0.862	1.37	0.38-4.86
	Additive	0.054	1.33	1.11-1.60	0.296	0.90	0.75-1.08	0.984	1.01	0.72-1.42
T2DM	Recessive	0.086	2.08	1.22-3.52	0.001	2.72	1.64-4.50	0.007	2.26	1.70-3.01
	Additive	0.050	2.09	1.63-2.69	< 0.001	2.85	1.74-4.65	0.011	2.30	1.74-3.06

All associations were tested using logistic regression adjusting for age, gender, smoking habits and physical activity. BMI: body mass index, HT: hypertension; LDL-C: Low density lipoprotein-cholesterol; T2DM: Type 2 diabetes mellitus. Bonferroni correction was made multiplying by 7 comparisons (Pc). Significant p values are in bold.