Table 3. . Multimodal MRI biomarkers associated with 1p/19q co-deletion.

Study	n	Histology	MRI features	Ref.
Chawla S et al.	40	WHO grade II and III OD	rCBVmax and metabolite ratios	[13]
Emblem K et al.	52	WHO grade II and III OD and OA	High rCBV	[32]
Fellah S et al.	50	WHO grade II and III OD and OA	Higher rCBV and rCBF within grade II oligodendroglial subgroup	[28]
Jenkinson MD et al.	37	WHO grade II and III OD and OA	Higher rCBV (>1.59)	[27]
Jenkinson MD et al.	17	WHO grade II and III OD and OA	Lower maximum and histogram ADC Lower ATC	[38]
Khayal IS et al.	30	WHO grade II AS, OD and OA	Lower median normalized ADC (<1.8)	[35]
Walker C et al.	59	WHO grade II and III OD and OA	Increased 201Tl uptake	[39]

ADC: Apparent diffusion coefficient; ATC: ADC transition coefficient; AS: Astrocytomas; OA: Oligoastrocytomas; OD: Oligodendroglioma; rCBF: Relative cerebral blood flow; rCBV: Relative cerebral blood volume.