Anda et al. (2008) |
Association between childhood adversity and Chronic Obstructive Pulmonary Disease (COPD) |
Quasi-prospective |
Adults |
15,472 |
Adverse Childhood Experiences (ACE; retrospective at baseline), COPD self-report, COPD incidence at follow-up, medication use at follow-up |
Brown et al. (2010) |
Association between childhood adversity lung cancer |
Quasi-prospective |
Adults |
17,337 |
ACE (retrospective at baseline), hospital discharge at follow-up, mortality records at follow-up, adult smoking as mediator |
Dong et al. (2004) |
Association between childhood adversity and ischemic heart disease (IHD) |
Retrospective |
Adults |
17,337 |
ACE, self-report of IHD, IHD risk factors (e.g., physical activity) as mediators |
Dube et al. (2001) |
Association between childhood adversity and suicide attempt |
Retrospective |
Adults |
17,337 |
ACE, self-report suicide attempt, illicit drug use, depression, and alcoholism as mediators |
Dube et al. (2009) |
Association between childhood adversity and autoimmune diseases (AD) |
Retrospective |
Adults |
15,357 |
ACE, hospitalization for 21 types of AD after baseline measurement of ACE, AD immunopathology grouping |
Felitti et al. (1998) |
Association between childhood adversity, health risk behaviors, obesity, and depression |
Retrospective |
Adults |
9,508 |
ACE, health risk behaviors and disease from self-report and health screening |
Miller and Chen (2010) |
Association between early life harsh family climate and pro-inflammatory phenotype in adolescence |
Prospective |
Female adolescents |
135 |
Harsh family climate, cytokine response to in-vitro bacterial challenge, sensitivity of glucocorticoid receptor |
Montez and Hayward (2014) |
Association between childhood adversity and active life expectancy |
Retrospective |
Adults |
30,671 |
Childhood health and SES, mortality, activities of daily living (ADL), educational attainment as mediator |
Norman et al. (2012) |
Association between childhood adversity and physical and mental health problems |
Meta-analysis |
Mixed |
>500,000 |
Physical abuse, sexual abuse, emotional and psychological abuse, neglect, depressive disorder, anxiety, alcohol abuse |
Sripada et al. (2014) |
Association between childhood poverty and stress reactivity in adulthood |
Case-control |
Adults |
52 |
Childhood poverty, Trier Social Stress Test, salivary cortisol |
Hughes et al. (2017) |
Association between childhood adversity an poor health in adulthood |
Meta-analysis |
Mixed |
253,719 |
ACE, cancer, heart disease, mental illness, drug use, and interpersonal and self-directed violence |
Varese et al. (2012) |
Association between childhood adversity and psychosis in adulthood |
Meta-analysis |
Mixed |
81,253 |
Childhood sexual abuse, physical abuse, emotional/psychological abuse, neglect, parental death, bullying, psychotic disorder, schizophrenia, schizoaffective disorder |
Huang et al. (2015) |
Association between childhood adversity and type 2 diabetes in adulthood |
Meta-analysis |
Mixed |
87,251 |
ACE, type 2 diabetes |
Infurna et al. (2016) |
Association between childhood abuse and neglect and depression |
Meta-analysis |
Adults |
4,372 |
Childhood experience of care and abuse (CECA), clinically assessed depression |
Lindert et al. (2014) |
Association between childhood sexual and physical abuse and depression |
Meta-analysis |
Mixed |
115,579 |
Sexual and physical abuse prior to 16 years of age, depression and anxiety after 16 years of age |
Palmier-Claus et al. (2018) |
Association between childhood adversity and bipolar affective disorder |
Meta-analysis |
Mixed |
>1,000,000 |
Child abuse, neglect, bullying, loss of parent, trauma, bipolar disorder |
Zatti et al. (2017) |
Association between childhood trauma and suicide attempt |
Meta-analysis |
Children → Adults |
6,612 |
Childhood sexual, physical, and emotional abuse, neglect, and suicide attempt |