Skip to main content
. Author manuscript; available in PMC: 2019 Aug 15.
Published in final edited form as: J Immunol. 2018 Jul 9;201(4):1287–1294. doi: 10.4049/jimmunol.1701459

FIGURE 1.

FIGURE 1

Intestinal CD11c+CX3CR1+ macrophages can induce B cells to produce IgA. (A) The expression of CX3CR1 were analyzed among CD11c+ cells of the small intestinal lamina propria from CX3CR1(GFP/+) mice. (B) Expression of CX3CR1, CD64, F4/80, CD11b and CD103 on lamina propria CD11c+ cells. (C and D) CD11c+ cells of small intestinal lamina propria from CX3CR1(GFP/+) mice were sorted to CX3CR1+ and CX3CR1− subsets. (C) Total IgA and (D) IgG level from culture supernatants of CX3CR1+ macrophages or CX3CR1− DCs co-cultured with B cells in presence of anti-IgM (10 µg/ml). Data are representative of three independent experiments. Graphs show mean ± SEM. ns; not significant, *p < 0.05 and **p < 0.01 using one-way ANOVA.