Table 2.

m-RESIST modules of intervention

Type of interversion	Basal intervention	Risk intervention
Aim	Oriented to develop abilities to deal with symptoms and early warning signs, to reinforce the involvement in the treatment plan, and to solve problems influenced by an unhealthy lifestyle.	Oriented to deal with possible situations of worsening (eg, detection of risk behaviours).
Modules	Integrated by three modules: symptoms management, treatment adherence and healthy lifestyle.	Integrated by one module: risk.
Core elements	Relapse signature identification, coping strategies selection.	Risk scale.
Activation triggers	External trigger: any of the modules can be activated by clinicians through the web-based platform (m-RESIST dashboard).	Internal trigger: when the system itself detects risk situations such as significant changes in threshold of specific sensor data. External trigger: patients or caregivers ask for help by the app’s alarm bottom.
Actions involved	Delivery of a basic set of questions by the app, to measure patients’ clinical status and appropriate follow-up questions or recommendations depending on the patients’ answers; use of reminders and psychoeducational content to help patients.	Delivery of appropriate questions, to check patient’s current condition and to send specific recommendations messages or notifications depending on the patients’ answers (by the app).

m-RESIST, mobile therapeutic attention for treatment-resistant schizophrenia.