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. 2018 Aug 8;13(8):e0201153. doi: 10.1371/journal.pone.0201153

Fig 1. Correlation of serum hepcidin levels with parameters of the iron status.

Fig 1

Serum hepcidin levels of the three patient groups of non-anemic controls, anemic patients treated with IV iron and anemic patients without IV iron treatment, were correlated to the iron parameters. The x- and y-scales are depicted logarithmic (log10). Values of “0” were replaced with 0.01 in order to depict them in the logarithmic graph. Serum hepcidin levels correlated with (A) serum iron levels (n = 146 XY-pairs (n = 9 non-anemics, n = 58 anemics without IV iron, n = 79 anemics plus IV iron); r = 0.19; Spearman *p = 0,02), (B) transferrin protein levels (n = 143 XY-pairs (n = 6 non-anemics, n = 58 anemics without IV iron, n = 79 anemics plus IV iron); r = -0,55; Spearman *p<0.0001), (C) ferritin levels (n = 143 XY-pairs (n = 6 non-anemics, n = 58 anemics without IV iron, n = 79 anemics plus IV iron); r = 0,75 Spearman *p<0.0001) and (D) transferrin saturation (n = 142 XY-pairs (n = 5 non-anemics, n = 58 anemics without IV iron, n = 79 anemics plus IV iron); r = 0.37; Spearman *p<0.0001).