Table 1. Probability ranges and corresponding coefficients of the beta prior densities for the sensitivities and specificities of the Kato-Katz and direct smear techniques used in the Bayesian latent class analyses to adjust for misclassification of STH infection.
Clinical priors | Optimistic priors | Pessimistic priors | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Range | Beta distribution coefficients | Range | Beta distribution coefficients | Range | Beta distribution coefficients | |||||
α | β | α | β | α | β | |||||
Kato-Katz | Ascaris: | |||||||||
Sensitivity | 0.55–0.75 | 55.86 | 29.63 | 0.70–0.80 | 214.34 | 70.81 | 0.50–0.60 | 208.45 | 170.38 | |
Specificity | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | |
Trichuris: | ||||||||||
Sensitivity | 0.75–0.90 | 77.85 | 15.75 | 0.85–0.95 | 116.06 | 12.05 | 0.70–0.80 | 214.34 | 70.81 | |
Specificity | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | |
Hookworm: | ||||||||||
Sensitivity | 0.52–0.68 | 85.65 | 56.78 | 0.63–0.73 | 226.28 | 105.98 | 0.47–0.57 | 198.73 | 183.37 | |
Specificity | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | |
Direct smear | Ascaris: | |||||||||
Sensitivity | 0.40–0.60 | 47.30 | 47.30 | 0.55–0.65 | 220.49 | 146.68 | 0.35–0.45 | 146.68 | 220.49 | |
Specificity | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | |
Trichuris: | ||||||||||
Sensitivity | 0.55–0.75 | 55.86 | 29.63 | 0.70–0.80 | 214.34 | 70.81 | 0.50–0.60 | 208.45 | 170.38 | |
Specificity | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | |
Hookworm: | ||||||||||
Sensitivity | 0.35–0.55 | 42.02 | 51.57 | 0.50–0.60 | 208.45 | 170.38 | 0.30–0.40 | 121.41 | 226.29 | |
Specificity | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 | 0.95–0.99 | 231.95 | 6.26 |