. 2018 Jul 31;7(2):111–118. doi: 10.7774/cevr.2018.7.2.111

Table 5. MTBC sensitivity and specificity compared with the reference results of culture, PCR, and sequencing (number of MTBC samples=473).

EZplex MTBC/ NTM Real-time PCR	Reference results (culture, PCR, sequencing)			Sensitivity (95% CI, %)	Specificity (95% CI, %)	PPV^a) (95% CI, %)	NPV^a) (95% CI, %)
EZplex MTBC/ NTM Real-time PCR	Positive	Negative	Total	Sensitivity (95% CI, %)	Specificity (95% CI, %)	PPV^a) (95% CI, %)	NPV^a) (95% CI, %)
Positive	213	3	216	98.6 (95.6–99.6)	98.8 (96.3–99.7)	98.6 (96.0–99.7)	98.8 (96.6–99.8)
Negative	3	254	257
Total	216	257	473

MTBC, Mycobacterium tuberculosis complex; PCR, polymerase chain reaction; NTM, nontuberculous mycobacteria; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.

^a)The PPV and NPV are the proportion of positive and negative results in diagnostic tests, considered as true positive and true negative results.