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. 2018 Jul 31;7(2):111–118. doi: 10.7774/cevr.2018.7.2.111

Table 6. NTM sensitivity and specificity compared with the reference results of culture, PCR, and sequencing (number of MTBC samples=396).

EZplex MTBC/ NTM Real-time PCR Reference results (culture, PCR, sequencing) Sensitivity (95% CI, %) Specificity (95% CI, %) PPVa) (95% CI) NPVa) (95% CI)
Positive Negative Total
Positive 139 0 139 100 (96.6–100) 100 (98.2–100) 100 (97.4–100) 100 (98.6–100)
Negative 0 257 257
Total 139 257 473

NTM, nontuberculous mycobacteria; PCR, polymerase chain reaction; MTBC, Mycobacterium tuberculosis complex; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value.

a)The PPV and NPV are the proportion of positive and negative results in diagnostic tests, considered as the true positive and true negative results.