Table 2.
Mean olfactory mucus levels of 14 different cytokines and inflammatory mediators for CRSwNP, CRSsNP, and healthy control subjects.
| Control | CRSsNP | CRSwNP | |||
|---|---|---|---|---|---|
|
| |||||
| Mean (range) | Mean (range) | p-value | Mean (range) | p-value | |
| IL-1β | 59.67 (0.335–295.7) | 143.2 (0.67–2351) | 0.97 | 94.38 (1.98–709) | 0.90 |
|
|
|||||
| IL-2 | 6.51 (0.07–46.0) | 95.54 (0.07–2797) | 0.59 | 19.55 (0.07–460) | 0.69 |
|
|
|||||
| IL-4 | 1.11 (0.005–6.22) | 0.42 (0.005–2.8) | 0.13 | 1.32 (0.005–14.5) | 0.85 |
|
|
|||||
| IL-5 | 0.52 (0.005–3.24) | 5.43 (0.005–83.3) | 0.23 | 42.46 (0.005–342.4) | <0.0001 |
|
|
|||||
| IL-6 | 94.73 (10.31–715.1) | 165.1 (1–2424) | 0.60 | 131.7 (2.94–1773) | 0.19 |
|
|
|||||
| IL-7 | 5.18 (0.63–14.4) | 2.74 (0.04–10.5) | 0.02 | 10.07 (0.3–55.1) | 0.57 |
|
|
|||||
| IL-8 | 3643 (118.9–22214) | 2673 (118.9–16532) | 0.40 | 4094 (282.7–32579) | 0.74 |
|
|
|||||
| IL-10 | 4.49 (0.07–9.3) | 10.27 (0.07–197.7) | 0.36 | 7.66 (0.07–69.2) | 0.99 |
|
|
|||||
| IL-12 | 128.3 (2.67–427) | 53.18 (0.04–257.1) | 0.23 | 94.52 (0.04–766.1) | 0.23 |
|
|
|||||
| IL-13 | 3.14 (0.005–17.2) | 2.51 (0.005–27.7) | 0.80 | 38.52 (0.005–334.9) | 0.01 |
|
|
|||||
| IL-17A | 1.66 (0.1–15.2) | 0.56 (0.1–6.07) | 0.50 | 7.94 (0.1–240.6) | 0.27 |
|
|
|||||
| Eotaxin | 18.16 (1.4–49.3) | 12.55 (0.065–44.1) | 0.11 | 18.45 (0.065–149.5) | 0.18 |
|
|
|||||
| TNF-α | 10.6 (0.025–63.1) | 8.99 (0.025–134.2) | 0.42 | 7.12 (0.025–7.12) | 0.85 |
|
|
|||||
| RANTES | 2500 (9.57–6600) | 1535 (18.97–6463) | 0.15 | 1675 (0.71–7471) | 0.26 |