Table 4.
Correlation between mucus cytokine levels of the olfactory cleft and age- and sex-adjusted SIT scores.
All CRS | CRSsNP | CRSwNP | ||||
---|---|---|---|---|---|---|
| ||||||
Spearman r | p value | Spearman r | p value | Spearman r | p value | |
IL-1β | −0.12 (−0.35–0.12) | 0.31 | −0.07 (−0.42–0.29) | 0.69 | −0.11 (−0.42–0.23) | 0.52 |
|
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IL-2 | −0.32 (−0.52– −0.09) | 0.006 | −0.24 (−0.55–0.13) | 0.18 | −0.19 (−0.49–0.14) | 0.25 |
|
||||||
IL-4 | 0.18 (−0.11–0.45) | 0.21 | ND | - | 0.16 (−0.17–0.46) | 0.32 |
|
||||||
IL-5 | −0.51 (−0.67– −0.31) | <0.0001 | −0.11 (−0.45–0.26) | 0.54 | −0.41 (−0.65– −0.09) | 0.01 |
|
||||||
IL-6 | −0.38 (−0.57– −0.16) | 0.0009 | −0.23 (−0.54–0.14) | 0.20 | −0.39 (−0.64– −0.08) | 0.01 |
|
||||||
IL-7 | −0.02 (−0.26–0.22) | 0.84 | 0.35 (−0.01–0.63) | 0.05 | −0.15 (−0.46–0.18) | 0.35 |
|
||||||
IL-8 | −0.12 (−0.35–0.12) | 0.32 | −0.08 (−0.43–0.28) | 0.66 | −0.10 (−0.41–0.23) | 0.53 |
|
||||||
IL-10 | −0.51 (−0.67– −0.31) | <0.0001 | −0.17 (−0.50–0.20) | 0.35 | −0.51 (−0.72– −0.23) | <0.001 |
|
||||||
IL-12 | −0.12 (−0.35–0.12) | 0.32 | −0.06 (−0.41–0.31) | 0.76 | −0.03 (−0.35–0.29) | 0.84 |
|
||||||
IL-13 | −0.46 (−0.63– −0.25) | <0.0001 | 0.15 (−0.22–0.48) | 0.41 | −0.51 (−0.71– −0.22) | 0.001 |
|
||||||
IL-17A | −0.10 (−0.39–0.20) | 0.49 | ND | - | −0.17 (−0.47–0.1) | 0.31 |
|
||||||
Eotaxin | −0.13 (−0.36–0.12) | 0.29 | 0.15 (−0.22–0.48) | 0.43 | −0.17 (−0.46–0.17) | 0.31 |
|
||||||
TNF-α | −0.17 (−0.39–0.07) | 0.16 | −0.03 (−0.39–0.33) | 0.85 | 0.08 (−0.26–0.39) | 0.65 |
|
||||||
RANTES | −0.01 (−0.25–0.23) | 0.93 | −0.13 (−0.47–0.24) | 0.47 | 0.15 (−0.19–0.45) | 0.38 |