Fig. 3.

UCMSCs attenuate sepsis-induced organ failure. Lung function was monitored by assessing the PaO₂/FIO₂ ratio (a) and based on histology (d). Renal function was assessed by measuring plasma creatinine concentration (b), fluid balance (c), and by histological observation (e). For histological scoring, a score of 0 corresponds to an absence of anomaly, 1 reflects discrete anomalies, 2 corresponds to moderate anomalies, and 3 indicates severe anomalies. Histological images (hematoxylin-eosin staining, × 40 magnification) are representative of the respective conditions. ^*p < 0.05; ^**p < 0.01;^***p < 0.001; ^****p < 0.0001 versus control group