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. 2018 Aug 8;8:11876. doi: 10.1038/s41598-018-30195-1

Figure 7.

Figure 7

Interaction interface in CYP3A4 dimer. The PDB stucture 1W0F was rendered using PyMOL. The F-G loop is shown in orange and residues Pro 218, Ser 222 and Ile 223 are shown in red. Progesterone molecules bound to the peripheral binding sites at the interface of the molecules are shown in magenta.