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. 2018 Aug 8;8:11873. doi: 10.1038/s41598-018-30373-1

Figure 2.

Figure 2

The mRNA expressions of LTB4 synthases in the skin and the effects of RvE1 on BLT1-deficient mice in the IMQ-induced psoriasis model. (a) The relative amount of Lta4h and Alox5 was measured by mRNA extracted from ear skin before and 3 h after topical IMQ application. (b) Ear thickness change was measured for five consecutive days after topical IMQ application in wild-type and BLT1-deficient mice treated daily with either vehicle or RvE1 (n = 3 per group). N.S indicates no significant difference. Data are representative of two independent experiments.