Comparative immune-histochemical expressions of p16 (A), Rb (B), β-catenin (C) and Pb (D) in aflatoxin-positive (AF+) and aflatoxin-negative (AF−) liver samples. HCC: hepatocellular carcinoma; VC: cirrhosis associated with viral hepatitis; AC: cirrhosis associated with alcoholism; NL: normal liver. n = 3 (HCC AF+), 5 (HCC AF-), 3 (VC AF+), 17 (VC AF−), 7 (AC AF+), 13 (AC AF−), 10 (NL). • Significant (P < 0.05) for comparisons between AF+ and AF− samples in each liver disorder. ° Significant (P < 0.05) for comparisons between NL and AF+ or AF− samples in all liver disorders.