Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 2;9:847. doi: 10.3389/fphar.2018.00847

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Zhang, Liu, Yu, Liu, Wang, Chen, Bian, Ji, Zhou, Chen, Ji, Xiang, Guo, Fang, Sun, Cao, Zhu and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Interfering or enforcing UBE2C expression affected cancer cell proliferation and invasion. (A) Protein level of UBE2C detected after siRNA transfection in BGC-823 cells. Among three siRNA sequences, si02 showed the best knockdown efficacy. (B) Knockdown of UBE2C decreased cell growth and colony formation in BGC-823 cells. (C) Knockdown of UBE2C decreased migration and invasion of BGC-823 cells. (D) Protein level of UBE2C detected after enforcing UBE2C expression in SGC-7901 cells. (E) Overexpression of UBE2C increased cell growth and colony formation in SGC-7901 cells. (F) Overexpression of UBE2C increased migration (upper) and invasion (lower) of SGC-7901cells. Experiments were performed in triplicates. *p < 0.05; **p < 0.01.