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. 2018 Feb 2;67(3):313–320. doi: 10.1538/expanim.17-0143

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©2018 Japanese Association for Laboratory Animal Science

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)

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Fig. 2. — Treatment with TXA relieved ALI of rats caused by T/HS. (A) Lung histological changes were examined by HE staining. (B) The ratio of the percentage of EBD in the BALF to EBD in the plasma. (C) Lung permeability index: BALF protein concentration /plasma protein concentration. a, Sham; b, T/HS group; c, pretreatment with TXA (50 mg/kg) + T/HS group; d, pretreatment with TXA (100 mg/kg) + T/HS group; e, T/HS + posttreatment with TXA (50 mg/kg) group; f, T/HS + posttreatment with TXA group (100 mg/kg). Data are presented as the mean ± SD. *P<0.05; ** P<0.01; ***P<0.001.