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Treatment with TXA inhibited inflammation of the lung in rats with T/HS. The levels of IL-6 and TNF-α in (A) BALF and (B) serum were detected. (C) MPO activity in lung tissue was evaluated. a, Sham; b, T/HS group; c, pretreatment with TXA (50 mg/kg) + T/HS group; d, pretreatment with TXA (100 mg/kg) + T/HS group; e, T/HS + posttreatment with TXA (50 mg/kg) group; f, T/HS + posttreatment with TXA group (100 mg/kg). Data are presented as the mean ± SD. *P<0.05; ** P<0.01; ***P<0.001.
