Table 2.

Number, Crude Incidence Rates per 100,000, and Annual Percent Change of the Top Five Cancers Diagnosed Among Adolescents and Young Adults by Gender and Age Group, Massachusetts 2004–2014

	Males					Females
	Number	Rate*	APC (95% CI)	p		Number	Rate*	APC (95% CI)	p
Age 15–24 years					Age 15–24 years
All cancers	1542	30.32	0.81 (−1.31 to 2.97)	0.41	All cancers	1674	33.24	1.15 (−0.74 to 3.07)	0.20
Germ cell and trophoblastic	372	7.31	3.62 (−1.63 to 9.16)	0.16	Thyroid	486	9.65	5.26 (1.67 to 8.98)	0.009
Hodgkin lymphoma	213	4.19	−0.13 (−4.43 to 4.36)	0.95	Hodgkin lymphoma	240	4.77	0.33 (−4.21 to 5.08)	0.88
Leukemia	169	3.32	0.38 (−3.30 to 4.20)	0.82	Melanoma of skin	216	4.29	04–08: 7.60 (−9.86 to 28.44)	0.35
								08–14: −18.22 (−27.40 to −7.87)	0.006
Non-Hodgkin lymphoma	153	3.01	0.25 (−4.14 to 4.85)	0.90	Central nervous system	118	2.34	2.21 (−5.34 to 10.36)	0.54
Central nervous system	119	2.34	5.00 (0.19 to 10.04)	0.043	Leukemia	98	1.95	2.18 (−4.32 to 9.11)	0.48
Ages 25–39 years					Ages 25–39 years
All cancers	5326	74.96	−0.55 (−1.51 to 0.43)	0.23	All cancers	9550	132.08	04–07: 4.30 (−0.94 to 9.82)	0.092
								07–14: −1.66 (−3.01 to −0.30)	0.025
Germ cell and trophoblastic	1051	14.79	−0.57 (2.62 to 1.52)	0.55	Breast	2508	34.69	−0.17 (−2.45 to 2.17)	0.87
Melanoma of skin	559	7.87	−5.33 (−7.85 to −2.74)	0.001	Thyroid	2419	33.46	04–06: 29.59 (7.21 to 56.63)	0.016
								06–14: 0.05 (−1.65 to 1.78)	0.95
Thyroid	515	7.25	5.83 (1.53 to 10.31)	0.013	Melanoma of skin	978	13.53	−4.43 (−7.50 to −1.26)	0.012
Non-Hodgkin lymphoma	449	6.32	−2.67 (−5.07 to −0.21)	0.037	Cervix and uterus	777	10.75	−2.69 (−5.14 to −0.18)	0.038
Colorectal	403	5.67	1.32 (−1.96 to 4.71)	0.39	Colorectal	393	5.44	2.31 (−0.93 to 5.66)	0.14

^*Rates are per 100,000; incidence rates are crude age-specific rates per 100,000; multiple annual percent change values are shown when the regression indicated a statistically significant breakpoint.

APC, annual percent change; CI, confidence interval.