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. 2018 Jul 26;2018:6579436. doi: 10.1155/2018/6579436

Table 2.

Signaling pathways in HCC regulated by lncRNAs.

lncRNAs Pathways Functions References
URHC ERK/MAPK pathway Regulates cell proliferation and apoptosis [53]
HULC RXRA pathway Modulates abnormal lipid metabolism [54]
LINC00152 mTOR pathway Promotes proliferation in HCC [55]
LINC01225 EGFR-dependent pathway Promotes occurrence and metastasis of HCC [56]
CCHE1 ERK/MAPK pathway Promotes carcinogenesis of HCC [57]
linc-cdh4-2 R-cadherin pathway Inhibits the migration and invasion of HCC cells [58]
lncARSR PTEN-PI3K/Akt Pathway. Promotes doxorubicin resistance in HCC [59]
TSLNC8 Interleukin-6/STAT3 pathway A tumor suppressor [60]
PDIA3P1 p53 pathway Promotes cell proliferation, migration and invasion, and suppresses apoptosis [61]
lncRNA00673 Notch pathway Promotes of proliferation and metastasis of HCC [62]
Igf2as ERK/MAPK pathway Controls hepatocellular carcinoma progression [63]
CCAL Wnt/β-catenin pathway Promotes HCC progression [64]
LncDQ EMT Pathway Promotes HCC progression [65]
lnc-Myd88 NF-κB and PI3K/AKT pathways Promotes HCC progression [66]