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Type I IFN responses are associated with altered cAMP and cGMP production in BMM and MDM. Metabolic genes identified as significantly altered (−1.2 ≤ FC ≥ 1.2, p value ≤ 0.05, FDR ≤ 0.1) were mapped to pathways associated with AMP and GMP production using MetScape and DAVID. Green and red represent genes that have been significantly upregulated or downregulated, respectively. Blue represents genes that were not altered following IFN-α stimulation.
