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. 2018 Jul 25;2018:9127146. doi: 10.1155/2018/9127146

Table 3.

Meta-analysis results of rs352140 based on five genetic models.

Genetic models OR (95% CI) p value Heterogeneity Effects model
I 2 (%) p value
Allele model (A versus G)
Overall 1.20 (0.97, 1.47) 0.09 83 0.00001 R
Race
 Chinese Han 1.46 (0.86, 2.48) 0.16 91 <0.0001 R
 Caucasian 1.11 (1.01, 1.22) 0.03 0 0.62 R

Dominant model (AA + GA versus GG)
Overall 1.30 (0.97, 1.74) 0.08 73 0.001 R
Race
 Chinese Han 1.54 (0.91, 2.61) 0.11 83 0.0006 R
 Caucasian 1.17 (0.91, 1.49) 0.22 17 0.30 R

Recessive model (AA versus GA + GG)
Overall 1.23 (0.81, 1.86) 0.34 77 0.0002 R
Race
 Chinese Han 1.35 (0.54, 3.39) 0.52 87 <0.0001 R
 Caucasian 1.20 (0.94, 1.51) 0.14 0 0.39 R

Heterozygous genetic model (GA versus GG)
Overall 1.24 (0.96, 1.59) 0.10 58 0.03 R
Race
 Chinese Han 1.42 (0.94, 2.15) 0.09 67 0.03 R
 Caucasian 1.09 (0.81, 1.49) 0.56 38 0.20 R

Homozygous genetic model (AA versus GG)
Overall 1.34 (0.83, 2.15) 0.23 78 0.0001 R
Race
 Chinese Han 1.53 (0.57, 4.15) 0.40 88 <0.0001 R
 Caucasian 1.30 (0.98, 1.73) 0.07 0 0.42 R

F: fixed-effect model; R: random-effect model; OR: odds ratio; 95% CI: 95% confidence interval.