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. 2001 Oct 30;98(23):13132–13137. doi: 10.1073/pnas.241504098

Figure 2.

Figure 2

rho-1(dn) can cause a cytokinesis defect. (A) Abnormally large neurons (flanked by arrows) in a living rho-1(dn) animal during the second larval stage. (B) Fluorescent visualization of the unc-47∷GFP-positive cells (flanked by arrows) in the animal shown in A. (C) Fluorescent visualization of unc-47∷GFP-positive neurons in a fixed rho-1(dn) animal. (D) DAPI visualization of the multiple nuclei observed in the unc-47∷GFP-positive cells shown in C. Arrowheads in C and D denote the positions of nuclei as determined by DAPI staining. Arrows in C and D show an unc-47∷GFP-positive cell without the cytokinesis defect. (Bar = 7 μm.) In wild-type animals (see Fig. 1A), multiple neurons are clearly visible in the same region of a multinuclear cell in the mutant.