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. 2018 Aug 2;9:332. doi: 10.3389/fpsyt.2018.00332

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Copyright © 2018 Shen, Song, Guo, Xu, Li, Zhang, Ma, Zhang, Lin, Li and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of repeated early-life sevoflurane exposure on behavior. (A) In the open field test, no significant difference was observed between the control group and the sevoflurane group in total distance moved. (B) A typical path during the probe trial for each group. (C) The latency to find the platform during the place navigation training phase of the Morris water maze test. (D) The percentage of time spent in the target quadrant during the probe trial of the Morris water maze test. N = 10 rats for each group. Repeated ANOVA with a post hoc least significant difference (LSD) test and unpaired t-tests were performed for (A,C,D), respectively; ^*p < 0.05. Data are presented as the mean ± SEM.