Table 1. Synthesis of isatinyl and indanyl nitrones.

Entry	R	R1	Y	X	MW (W)	Time (min)	Product	Yield (%)
1	Me	5-NO2	NH	CO	600	10	4a	95
2 a	Ph	H	NH	CO	600	10	4b	92
3	Bn	5-NO2	NH	CO	600	13	4c	92
4	Bn	H	NH	CO	600	12	4d	95
5	Bn	H	NMe	CO	600	12	4e	92
6	Me	H	CH2	CH2	400	30	5a	82
7	Me	5-F	CH2	CH2	400	28	5b	83
8	Bn	H	CH2	CH2	400	30	5c	85

^aA ketone/alkylhydroxylamine ratio of 1 : 2 for all substrates except for entry 2 with a ratio of 1 : 3.