Table 1. Antiproliferative activity data (IC50, μM) of chlordinaline against six cancer cell lines.
Compound | IC50
a
(μM) |
|||||
A549 | A375 | SMMC7721 | HepG2 | H1299 | H460 | |
Chlorambucil | 22.2 ± 3.7 | 69.2 ± 9.9 | 163.0 ± 20.7 | 111.8 ± 17.0 | 116.3 ± 24.8 | 28.9 ± 3.5 |
Tacedinaline | 20.1 ± 0.8 | 11.3 ± 1.1 | 16.9 ± 1.3 | 18.5 ± 1.8 | 33.8 ± 3.9 | 9.7 ± 1.1 |
Chlordinaline | 6.2 ± 1.3 | 6.1 ± 0.9 | 4.0 ± 0.6 | 14.2 ± 4.0 | 5.5 ± 1.3 | 3.1 ± 0.2 |
aThe values represent the means of three experiments.