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. 2017 Dec 27;9(2):344–352. doi: 10.1039/c7md00476a

Table 1. Antiproliferative activity data (IC50, μM) of chlordinaline against six cancer cell lines.

Compound IC50 a (μM)
A549 A375 SMMC7721 HepG2 H1299 H460
Chlorambucil 22.2 ± 3.7 69.2 ± 9.9 163.0 ± 20.7 111.8 ± 17.0 116.3 ± 24.8 28.9 ± 3.5
Tacedinaline 20.1 ± 0.8 11.3 ± 1.1 16.9 ± 1.3 18.5 ± 1.8 33.8 ± 3.9 9.7 ± 1.1
Chlordinaline 6.2 ± 1.3 6.1 ± 0.9 4.0 ± 0.6 14.2 ± 4.0 5.5 ± 1.3 3.1 ± 0.2

aThe values represent the means of three experiments.