Effects of 4 MM ± L-DOPA, PARG or METH on markers of striatal dopaminergic toxicity. Levels of (A) DA, (B) DAT, and (C) TH were determined in the striatum following treatment with 4 MM, +/−L-DOPA (L–D), pargyline (PARG), or METH. *p < 0.05 **p < 0.01 ****p < 0.0001 compared to controls. ##p < 0.01 ###p < 0.001 ####p < 0.0001 compared to 4MM. @@@ p < 0.001 @@@@ p < 0.0001 compared to METH. Data are presented as mean + SEM. N = 5–16 mice per group.