Table 3. Synthesis of fluororibonucleosides 23.
Entry | R | Conditions | Product | Yield [%] |
1 | NH2 | g | 23a | 82 |
2 | OMe | h | 23b | 80 |
3 | SMe | i | 23c | 87 |
4 | Me | j | 23d | 65 |
5 | 2-Furyl | k | 23e | 12 |
6 | 3-Furyl | k | 23f | 50 |
7 | 2-Thienyl | k | 23g | 70 |
8 | 3-Thienyl | k | 23h | 40 |
9 | Phenyl | k | 23i | 41 |