Table 3.

24-month rCMRgl declines in amyloid-β positive dementia-AD patients compared to amyloid-β negative cognitively unimpaired controls.

Region		k	p(unc)	MNI (mm)
				x	y	z
R	Inferior Parietal Lobule	11,225	3.51E-07⁎	58	−50	52
R	Inferior Parietal Lobule		4.39E-07	52	−56	52
R	Inferior Temporal Gyrus		8.30E-07	58	−48	−14
L	Middle Temporal Gyrus	6845	9.79E-07⁎	−62	−46	−14
L	Inferior Parietal Lobule		1.74E-06	−60	−44	48
L	Middle Temporal Gyrus		6.41E-06	−52	−70	22
L	Precuneus	4067	5.15E-06⁎	0	−68	44
L	Cingulate Gyrus		5.64E-06	−2	−34	30
L	Precuneus		0.0002	−6	−46	34
L	Caudate	125	0.0003	−10	10	8
L	Middle Frontal Gyrus	347	0.0009	−26	28	60
L	Superior Frontal Gyrus		0.0014	−16	10	76
L	Middle Frontal Gyrus		0.0004	−30	14	64
R	Middle Frontal Gyrus	460	0.0006	38	12	64
R	Middle Frontal Gyrus		0.0007	44	4	66

Results are listed at p < .005 uncorrected and a cluster size threshold of 100 continuous voxels. Bold data indicate primary peaks within a cluster, non-bold data indicate secondary peaks within the cluster. MNI: Montreal Neurological Institute; p(unc): uncorrected p-value; k: cluster size.

^⁎p < .05 FWE corrected on the cluster-level.