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. 2018 Aug 2;9:1031. doi: 10.3389/fphys.2018.01031

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Copyright © 2018 Ørtenblad, Nielsen, Boushel, Söderlund, Saltin and Holmberg.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mitochondria content and subcellular localization in distinct fiber types and at whole-muscle level of leg and arm muscles. There was a tendency (P = 0.095) toward a higher mitochondrial content in the intermyofibrillar (IMF) and subsarcolemmal (SS) regions, of arm muscle (open bars) compared with leg muscle (filled bars) (A). This tendency is also apparent when calculating total mitochondrial content (IMF + SS) (B). (C) Weighted mitochondrial volumes in the arm and leg muscle, estimated from a fiber type distribution of 57 and 37% MHC-I for the leg and arm (n = 9), respectively. These MHC weighted values of whole-muscle mitochondrial content in arm and leg muscles are similar. Values are means ± SE (n = 29–30 fibers from 10 subjects).