Table 3. The predictive and tested IC50s against B-Raf of the screened natural products quercetin and myricetin.
Compound | Pred.-pIC50 | Pred. IC50 (nM) | Experimental IC50 (μM) |
Quercetin | 8.13 | 7.41 | 7.589 |
Myricetin | 7.18 | 66.07 | 1.562 |
GW5074 | — | — | 0.0015 |