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. 2018 Aug 7;28(2):256–267.e5. doi: 10.1016/j.cmet.2018.05.021

Figure 4.

Figure 4

Sex-Specific Liver Metabolome Is Associated with Neonatal Estrogen Signaling

(A and B) PCA (A) and hierarchical clustering heatmap (B) measured at P1 in the liver of males and females treated with vehicle (VEH) or 1 mg/kg Arimidex (Ar).

(C–E) Quantitative analysis of the metabolites measured in the liver of 3-month-old adult male and female ArKO (aromatase KO) mice. Data represent mean ± SEM (n = 3).