Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug;76:295–307. doi: 10.1016/j.actbio.2018.05.053

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Elsevier Ltd. All rights reserved.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 4 — Tissue mineralization: (A) BSE images of transverse cross sections of tibia mid-diaphysis from Crh^+/+ and Crh^−120/+ mice bone with different ages (8, 12, 24 and 36 weeks). (B) Transverse cross section of mid-shaft femora from Crh^−120/+ mice aged 24 weeks. Periosteal region and endosteal region with halos (dashed line) are indicated. (C) BSE image of longitudinal section of mid-shaft femora from Crh^+/+ (upper) and Crh^−120/+ mice (lower) aged 24 weeks. (D) Histograms of mineral concentration obtained from X-ray tomography images of transverse cross section of mid-shaft femora from Crh^+/+, Crh^−120/+ bone, and Crh^−120/+ periosteal and endosteal regions aged 24 weeks. (E) Mean mineral concentration as a function of developmental ages for Crh^+/+, Crh^−120/+ periosteal regions and Crh^−120/+ endosteal regions. (F) Mean mineral concentration as a function of development age (weeks) for Crh^+/+ (black circles) and Crh^−120/+ mice (red triangles (colour online), including both periosteal and endosteal regions). Error bars shown are standard deviations. Statistical significance is denoted (*p < 0.05, **p < 0.01, ***p < 0.001, ns: not significant). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)