Table 2.
LH/FSH ratio | Q1 | Q2 | Q3 | Q4 | P for trend |
---|---|---|---|---|---|
≤0.32 | 0.33–0.39 | 0.40–0.47 | ≥0.48 | ||
N | 641 | 645 | 624 | 615 | |
Age (year) | 65.31 ± 6.96 | 64.53 ± 6.76 | 63.87 ± 6.32 | 63.42 ± 6.16 | < 0.001 |
METABOLIC FACTORS | |||||
Waist circumference (cm) | 80.33 ± 9.89 | 80.85 ± 9.43 | 81.76 ± 9.48 | 83.30 ± 10.17 | < 0.001 |
Waist-hip ratio | 0.87 ± 0.08 | 0.87 ± 0.08 | 0.87 ± 0.17 | 0.88 ± 0.08 | 0.05 |
Body mass index (kg/m2) | 24.43 ± 3.57 | 24.68 ± 3.59 | 25.07 ± 3.47 | 25.64 ± 3.84 | < 0.001 |
Visceral adiposity index | 1.61 (1.58) | 1.83 (1.52) | 1.93 (1.50) | 1.97 (1.63) | < 0.001 |
Chinese visceral adiposity index | 105.87 ± 32.15 | 107.26 ± 31.78 | 109.98 ± 30.91 | 114.13 ± 32.54 | < 0.001 |
Lipid accumulation product | 30.38 (31.44) | 33.82 (32.27) | 34.12 (33.70) | 37.41 (36.66) | < 0.001 |
Systolic pressure (mmHg) | 138.93 ± 20.81 | 138.32 ± 21.50 | 141.73 ± 22.20 | 142.41 ± 22.67 | < 0.01 |
Diastolic pressure (mmHg) | 78.89 ± 11.90 | 78.89 ± 12.50 | 80.97 ± 13.10 | 81.63 ± 12.73 | < 0.001 |
Fasting glucose (mmol/L) | 5.86 ± 1.31 | 5.92 ± 1.78 | 5.80 ± 1.41 | 5.89 ± 1.62 | 0.53 |
Fasting insulin (pmol/L) | 32.50 (21.70) | 33.90 (25.30) | 36.60 (22.90) | 37.00 (26.60) | < 0.05 |
HOMA-IR | 1.18 (0.88) | 1.23 (0.98) | 1.33 (0.96) | 1.33 (1.11) | 0.06 |
TG (mmol/L) | 1.32 (0.91) | 1.48 (0.96) | 1.48 (0.94) | 1.48 (0.95) | < 0.01 |
TC (mmol/L) | 5.49 ± 1.11 | 5.49 ± 1.04 | 5.46 ± 1.31 | 5.48 ± 1.14 | 0.86 |
LDL (mmol/L) | 3.18 ± 0.78 | 3.25 ± 0.79 | 3.33 ± 0.82 | 3.42 ± 0.87 | < 0.001 |
HDL (mmol/L) | 1.54 ± 0.34 | 1.51 ± 0.33 | 1.44 ± 0.31 | 1.41 ± 0.31 | < 0.001 |
SEX HORMONES | |||||
Total T (proportion above vs. below detection limit, %) | 28.5 vs. 71.5 | 33.2 vs. 66.8 | 36.7 vs. 63.3 | 42.6 vs. 57.4 | < 0.001 |
E2 (proportion above vs. below detection limit, %) | 32.6 vs.67.4 | 32.6 vs. 67.4 | 28.5 vs. 71.5 | 33.3 vs. 66.7 | 0.249 |
LH (IU/L) | 18.5 (10.3) | 23.1 (10.6) | 25.3 (12.9) | 31.1 (14.4) | < 0.001 |
FSH (IU/L) | 66.4 (33.0) | 63.4 (29.8) | 59.4 (29.7) | 53.8 (25.5) | < 0.001 |
Current smoker (%) | 4.7 | 3.1 | 3.1 | 3.2 | 0.33 |
Data are summarized as the mean ± standard deviation or median (interquartile range) for normally or non-normally distributed continuous variables and as the number with proportion for categorical variables. ANOVA and Kruskal-Wallis test were used for continuous variables, and the Pearson χ2 test was used for dichotomous variables.