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. 2018 Jul 13;9(54):30240–30252. doi: 10.18632/oncotarget.25367

Figure 5. Lamp2 represses the epithelial-mesenchymal transition in HCC cells.

Figure 5

(A, B and C) Western blot analysis and RT-PCR reveal downregulation of the expression of epithelial markers (E-cadherin and ZO-1) and upregulation of the expression of mesenchymal markers (Vimentin and N-cadherin) in Huh7 andHepG2 cells transfected with Lamp2 siRNA. In contrast, (A) Western blot analysis and (D–E) RT-PCR reveal that Lamp2 overexpression upregulated the expression of epithelial markers and decreased the expression of mesenchymal markers in Huh7 andHepG2 cells. Scale bar indicates 25 μm.