. 2018 Jul 13;9(54):30240–30252. doi: 10.18632/oncotarget.25367

Table 1. Correlation of the Lamp2 protein level in HCC tissues with clinicopathological characteristics.

Factors	Lamp2 expression		χ²	P-value
Factors	High	Low	χ²	P-value
Gender
Male	132	126	1.425	0.233
Female	11	17	1.425	0.233
Age (years)
> 55	60	64	0.228	0.633
≤ 55	83	79	0.228	0.633
AFP (ng/Ml)
> 20	51	84	15.279	< 0.001^#
≤ 20	92	59	15.279	< 0.001^#
HBsAg
Positive	125	122	0.267	0.605
Negative	18	21	0.267	0.605
Liver cirrhosis
Present	87	92	0.373	0.541
Absent	56	51	0.373	0.541
Tumor number
Multiple	43	45	0.066	0.798
Solitary	100	98	0.066	0.798
Tumor size (cm)
> 5	82	84	0.057	0.811
≤ 5	61	59	0.057	0.811
Capsular formation
Present	89	70	5.113	0.024^#
Absent	54	73	5.113	0.024^#
Microvascular invasion
Present	61	93	14.407	< 0.001^#
Absent	82	50	14.407	< 0.001^#
Edmondson-Steiner grade
Low grade (I and II)	22	15	1.521	0.217
High grade (III and IV)	121	128	1.521	0.217
TNM Stage
I	92	90	0.06	0.806
II–III	51	53	0.06	0.806
BCLC Stage
A+B	77	80	0.127	0.721
C+D	66	63	0.127	0.721

Values shown with ^# are statistically significant (p < 0.05).

The median expression level was used as the cutoff value. Low Lamp2 expression in each of the 143 patients was defined as a value below the 50th percentile. High Lamp2 expression in each of the 143 patients was defined as a value above the 50th percentile.

Pearson's Chi-square tests were used for the correlation analysis between the expression levels of Lamp2 and clinical features. The results were considered statistically significant at p < 0.05.