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. 2018 Jul 13;9(54):30450–30464. doi: 10.18632/oncotarget.25765

Figure 3. Response of melanoma cells to Chk1 inhibitor PF477736.

Figure 3

(A) and (B) A375-PLX-R melanoma cell is more sensitive to PF477736 than A375 in both cell viability and colony formation assays. (C) and (D) WM9-PLX-R melanoma cell is less sensitive to PF477736 than WM9 in both cell viability and colony formation assays. One-day post-seeding, the cells were treated with various concentrations of PF477736 or DMSO for 48 h. Cell viability and colony formation were measured as described in MATERIALS AND METHODS. The error bars reported in (A) and (C) are the standard deviations of the averages from triplicates of three independent experiments.