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. Author manuscript; available in PMC: 2019 May 15.
Published in final edited form as: Cancer Res. 2018 Mar 14;78(10):2760–2769. doi: 10.1158/0008-5472.CAN-17-2538

Fig 2. AP-2α promoted tumor MPO transcription by binding to the rs2333227 T genotype in CRC patients.

Fig 2

(A–C) The binding affinity between AP-2α and the indicated MPO rs2333227 genotypes were determined by ChIP assay in CRC Human peripheral white blood (A), SW620 cells (B) and SW480 cells (C). (D) MPO mRNA levels in CRC tissues expressing CC or CT/TT genotype were detected by qPCR analysis. (E) MPO protein levels in CRC tissues expressing CC, CT or TT genotype were detected by immunobloting. ***P < 0.001.