. Author manuscript; available in PMC: 2019 May 15.

Published in final edited form as: Cancer Res. 2018 Mar 14;78(10):2760–2769. doi: 10.1158/0008-5472.CAN-17-2538

Table 1.

Association between the MPO polymorphisms and risk of CRC

SNPs	genotype	Cases		Controls		P	Adjusted OR(95%CI)^a

		n	%	n	%
rs2243828	AA	714	66.2	787	67	0.3981	1.00(ref)
	AG	308	28.6	341	29		0.99(0.82–1.19)
	GG	56	5.2	47	4		1.33(0.89–1.99)
	HWE	0.0034		0.1924
	P trend					0.4212
rs2333227	CC	746	69.2	875	74.5	0.0066	1.00(ref)
	CT	300	27.8	281	23.9		1.27(1.05–1.53)
	TT	32	3	19	1.6		2.00(1.12–3.56)
	CC	746	69.2	875	74.5	0.0054	1.00(ref)
	CT/TT	332	30.8	300	25.5		1.31(1.09–1.58)
	T allele	0.1688		0.1357		0.002
	HWE	0.7824		0.5097
	P trend					0.002

Adjusted for age, gender, smoking and drinking status.