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. 2018 Jun 28;126(6):067009. doi: 10.1289/EHP3368

Figure 3.

Figure 3A is a tabular representation for curation and extraction for peer-reviewed reference doses listing inclusion criteria, exclusion criteria, and data and metadata extracted. Figure 3B is a tabular representation for conceptual models and magnitudes of effect for different types of endpoints listing continuous endpoints, quantal-deterministic endpoints, quantal-stochastic endpoints, and multiple endpoints.

Details of (A) toxicity value curation and data extraction and (B) assignment of conceptual model based on type of effect. Note: BMD, Benchmark Dose; BMDL, Benchmark Dose Lower Confidence Limit; BMR, Benchmark Response; CASRN, Chemical Abstracts Service Registry Number; ED50, Effective Dose for a 50% response; LOAEL, Lowest Observed Adverse Effect Level; MRL, Minimal Risk Level; NOAEL, No Observed Adverse Effect Level; POD, Point of Departure; RfD, Reference Dose; SD, Standard Deviation; SE, Standard Error; UF, Uncertainty factor. See WHO/IPCS (2014) and Chiu and Slob (2015) for detailed definitions and descriptions of each conceptual model.