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. 2018 Aug 9;13(8):e0201589. doi: 10.1371/journal.pone.0201589

Table 4. Serum concentrations of interleukins 6 and 18, 25-hydroxyvitamin D3, and cortisol in all participants (N = 150) according to depression severity.

No depression (mean ± SD; n = 112) Mild depression (mean ± SD; n = 25) Moderate depression (mean ± SD; n = 13) p
Interleukin 6
(pg/ml)
0.74 ± 0.88 3.9 ± 3.8 5.0 ± 6.0 0.001
Interleukin 18 (pg/ml) 2.1 x102 ± 0.9 x 102 2.6 x 102 ± 0.4 x 102 3.8 x 102 ± 1.1 x 102 <0.001
25-hydroxyvitamin D3 (ng/ml) 19.7 ± 8.9 12.0 ± 3.5 9.2 ± 3.5 <0.001
Cortisol (ng/ml) 1.2 x 102 ± 0.4 x 102 1.4 x 102 ± 0.5 x 102 1.2 x 102 ± 0.1 x 102 0.31

SD, standard deviation