Table 4. Serum concentrations of interleukins 6 and 18, 25-hydroxyvitamin D3, and cortisol in all participants (N = 150) according to depression severity.
No depression (mean ± SD; n = 112) | Mild depression (mean ± SD; n = 25) | Moderate depression (mean ± SD; n = 13) | p | |
---|---|---|---|---|
Interleukin 6 (pg/ml) |
0.74 ± 0.88 | 3.9 ± 3.8 | 5.0 ± 6.0 | 0.001 |
Interleukin 18 (pg/ml) | 2.1 x102 ± 0.9 x 102 | 2.6 x 102 ± 0.4 x 102 | 3.8 x 102 ± 1.1 x 102 | <0.001 |
25-hydroxyvitamin D3 (ng/ml) | 19.7 ± 8.9 | 12.0 ± 3.5 | 9.2 ± 3.5 | <0.001 |
Cortisol (ng/ml) | 1.2 x 102 ± 0.4 x 102 | 1.4 x 102 ± 0.5 x 102 | 1.2 x 102 ± 0.1 x 102 | 0.31 |
SD, standard deviation