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. 2018 Aug 9;13(8):e0201755. doi: 10.1371/journal.pone.0201755

Table 1. Univariate relationships between clinical parameters and presence of nodal metastasis.

Clinical parameter Cancer absent in nodes(N = 434) cancer present in nodes(N = 189) P-value (Chi-Square test)
N (%) N (%)
Age
    40 or below 18 (64.3) 10 (35.7)
    41 or more 415 (70) 178 (30.0) 0.52
Sex
    female 106 (70.7) 44 (29.3)
    male 328 (69.3) 145 (30.7) 0.76
Primary site of cancer
    Buccal mucosa 239 (76.4) 74 (23.6)
    Tongue 195 (62.9) 115 (37.1) <0.01
Pattern of invasion (POI)
    I 1 (100) 0 (0.0)
    II 92 (88.5) 12 (11.5)
    III 176 (78.2) 49 (21.8)
    IV 164 (56.2) 128 (43.8) <0.01
Size of the tumour (T)
    T1 63 (92.6) 5 (7.4)
    T2 160 (81.6) 36 (18.4)
    T3 99 (60.4) 65 (39.6)
    T4 112 (58.0) 81 (42.0) <0.01
Depth of invasion (DOI)
    1 to <2mm 38 (76.0) 12 (24.0)
    2 to <3mm 59 (79.7) 15 (20.3)
    3 to <4mm 64 (86.5) 10 (13.5)
    4 to <5mm 39 (75.0) 13 (25.0)
    5+mm 233 (63.3) 135 (36.7) <0.01
Depth (non-censored cases only, n = 385)
    1 to <2mm 32 (74.4) 11 (25.6)
    2 to <3mm 49 (83.1) 10 (16.9)
    3 to <4mm 47 (87.0) 7 (13.0)
    4 to <5mm 21 (84.0) 4 (16.0)
    5+mm 137 (67.2) 67 (32.8) 0.009

Percentage (%) is the row percentage. POI type 1 group not used in Chi-Square test due to single person in it. Frequencies may not sum to total shown in column heading due to missing values.